Status As of August 8, 2026, no DEA temporary scheduling order for 7-OH has been published in the Federal Register. The earliest lawful effective date was August 5, 2026 — an order may publish any day. Track the docket →
Eusomnia 7-OH Resource

About the author, and how to reach me

It would be strange to describe a crisis at length and then not offer to do anything about it. Below is who wrote this, what the clinical experience behind it actually consists of — stated with its limits — what is on offer, and how to get in touch.

Brian Harris, MD Addiction Medicine Anesthesiology Sleep Medicine EusomniaMD
If you need help right now

This page is not an emergency service and messages are not monitored continuously. If someone is difficult to wake, breathing slowly or abnormally, making choking or gurgling sounds, or turning blue or grey: give naloxone if available and call 911. For poisoning advice, call 1-800-222-1222. For crisis support, call or text 988. To find treatment now, use FindTreatment.gov or read the patient and family guide.

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Brian Harris, MD

Physician board certified in Addiction Medicine, Anesthesiology, and Sleep Medicine, and founder of EusomniaMD. Clinical work covers assessment and treatment of substance use disorders, opioid dependence, withdrawal and medication treatment, sleep disorders, and the interaction between sleep, sedating drugs, and respiratory risk — a combination that turns out to be unusually relevant to a drug class whose principal acute danger is respiratory depression and whose principal withdrawal complaint is insomnia.

In 2025 he served as faculty for the California Society of Addiction Medicine's Addiction Medicine Board Exam Preparation Course, teaching Basic Science (Neurobiology) and Legal Aspects of Addiction Medicine. CSAM's public faculty listing confirms those teaching roles, the three board certifications, and that no relevant financial relationships were reported for that CME activity.E41

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Practice-based 7-OH experience

Direct treatment of a practice-based case series in the teens involving botanical kratom, concentrated 7-OH, or both — ranging from relatively uncomplicated dependence to severe, high-frequency, high-dose use. Informal clinician consultation on dozens of additional 7-OH withdrawal and treatment cases.E48

The people represented in that experience have not fit one demographic stereotype. They have included younger and older adults, men and women, professionals and people with limited resources, patients with and without prior conventional opioid exposure, and healthcare professionals, including physicians. That range is itself clinically informative: it is why a screening question aimed only at people who look like they use opioids will miss most of this population.

This experience is useful because the formal literature remains small and the commercial market has changed faster than conventional guideline development can follow. It is not a substitute for research, and it is not offered as one.

What this case series is not

It is unpublished. It is not an IRB-reviewed research cohort. It is not a prevalence or incidence estimate. It is not proof of a universal withdrawal timeline. It is not evidence that one induction method is best for every patient.

Throughout this resource it is labelled Practice-based synthesis and graded D. Published cases, case series, controlled studies, analytical chemistry, toxicology, and official regulatory documents are cited separately and carry their own grades in the evidence library.

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Why offer a clinical framework before perfect data exist

Waiting for a large prospective trial would be scientifically comfortable and clinically useless to patients losing access now. The responsible middle position is to state what is known, identify what is extrapolated, show the limits of every claim, and still give clinicians a structured way to assess risk and apply established opioid use disorder treatment principles.

What follows from that is a practice-based clinical framework, not a national guideline. It is designed to be corrected as direct 7-OH evidence accumulates, and the corrections will be dated and visible rather than silent.

Every claim on this site is graded. Where the honest answer is that nobody knows, the site says nobody knows.
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Clinical and educational services

Clinician-to-clinician consultation

Kratom and 7-OH exposure history, withdrawal assessment, buprenorphine initiation strategy, precipitated-withdrawal risk, differential diagnosis, and level-of-care decisions. Curbside consultation between colleagues, not a formal referral.

Ask a clinical question

Patient evaluation and treatment

Where legally and clinically appropriate. Subject to licensure, jurisdiction, capacity, and individualised assessment. If you are looking for care and cannot find a prescriber, say so and you will be helped to look.

Patient & family guide

Programme & workflow development

Development or review of workflows for detoxification centres, emergency departments, outpatient programmes, and residential treatment facilities — including intake screening, toxicology ordering, and regulatory-transition planning.

Request a review

Teaching & grand rounds

Grand rounds, conference lectures, fellow and resident teaching, and public-health presentations. The neurobiology material taught at CSAM in 2025 adapts readily for board preparation or for a general clinical audience. In person in the Bay Area, or by video.

Invite a lecture

Press & media

Available to journalists covering the scheduling action for background, on-record comment, or technical review of a draft before publication. The clinical half of this story is being reported thinly, and accurate coverage is genuinely protective.

Press enquiry

Employers & occupational health

Guidance for organisations with drug-testing programmes, safety-sensitive roles, or employee assistance responsibilities — including the fact that standard opiate panels do not detect these compounds, and what a defensible policy looks like once they are scheduled.

Discuss a policy

Clinical services are subject to licensure, jurisdiction, capacity, and individualised assessment. Educational material is not a substitute for emergency care or for a treating clinician.

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Editorial position

This project supports decisive regulation of concentrated and semisynthetic 7-OH products. It also holds that removing a widely available opioid product without a treatment bridge creates avoidable harm. Those two positions are not in tension, and anyone who insists they are is arguing about something else.

The purpose of this resource is not to defend the commercial 7-OH market, to create a proprietary detoxification brand, or to make sparse data look abundant. It is to reduce overdose, untreated withdrawal, illicit-opioid substitution, and preventable clinical confusion during a rapidly changing public-health event.

The full argument, and what to do about it →

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Disclosure and corrections

For the 2025 CSAM CME activity, the official course listing states that no relevant financial relationships were disclosed.E41 A course-specific disclosure should not be silently extended to cover all later activity, so a current, resource-specific disclosure is posted separately below.

Resource-specific disclosure

No financial relationship with any kratom, 7-OH, or dietary-supplement manufacturer, distributor, retailer, trade association, or advocacy organisation. No pharmaceutical industry funding for this resource. No sponsored links. This site is self-published and self-funded. Clinical services described above are offered through EusomniaMD, a private practice.

Suspected errors, missing sources, or potential conflicts may be reported directly. Material corrections are dated and logged rather than silently applied — that policy is part of why a sceptical colleague should be willing to trust the rest of the site. See the evidence library for how each claim is graded.

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Contact

Please state in your first message which category you are writing about — clinical consultation, patient referral, programme development, teaching, press, or a correction — so that urgent clinical questions can be prioritised.

Direct

Brian Harris, MD · EusomniaMD

Before writing

Three practical notes

This is not an emergency service. Messages may not be seen for some time. If you or someone you are with is in danger, call 911.

Do not send protected health information or identifiable patient details through unsecured email. Describe the clinical question without identifiers and a secure channel can be arranged.

Contact does not create a physician–patient relationship. Correspondence about a case is collegial consultation to the treating clinician, who retains responsibility for the patient.

Share it

The most useful thing you can do is forward this to whoever will see the first case